Metabolic diseases of liver

A number of metabolic conditions involve the liver and can cause chronic liver disease, leading to cirrhosis and liver cancer. The three most common metabolic liver diseases are: hereditary hemochromatosis, Alpha-I antitrypsin deficiency (AATD), and Wilson Disease. Hereditary hemochromatosis, also called iron overload disease, is genetic disorder in which the body absorbs and stores too much iron. Iron overload may also occur when the body receives many blood or intravenous iron infusions. The iron deposits in the liver, pancreas and other organs, which can cause cirrhosis of the liver. Iron overload can be diagnosed with simple blood tests. Alpha-I antitrypsin deficiency (AATD) is a rare genetic condition that often causes emphysema in adults and/or liver disease at any age.

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